| Titre : | A case report on elderly psychotic-like symptoms caused by antidepressant discontinuation (2022) |
| contenu dans : | |
| Auteurs : | TSAI LEE-HOU ; LIN JENG-WEN |
| Type de document : | Article |
| Dans : | ANNALES MEDICO PSYCHOLOGIQUES (7 vol 180, 2022) |
| Article en page(s) : | 664-669 |
| Note générale : | 15 réf. bibliogr. / Fig. / Tabl. / Article en anglais |
| Descripteurs |
[SANTEPSY] ABANDON DU TRAITEMENT [SANTEPSY] ANTIDEPRESSEUR [SANTEPSY] CAS CLINIQUE [SANTEPSY] DEPRESSION [SANTEPSY] PERSONNE AGEE |
| Mots-clés libres: | PAROXETINE |
| Résumé : | Objectives : Cure for severe depression in elderly patients with psychotic symptoms should consider not only the results of major depression but also the nature of antidepressants and their side effects. Psychiatric disability is higher in patients who have greater deterioration in neurological function. Methods : In addition to reviewing antidepressant discontinuation syndrome and depressive disorder, this study describes an elderly woman with mild depression that developed into major depression, related to high suspicion of delirium, diagnosed based on patient history, physical health examination, neurological examinations, family history, and laboratory data, with subsequent treatment plan. Results : The treatment results and prognosis indicate that patients with paroxetine antidepressant deactivation may enable early use of low-dose quetiapine with less anticholinergic and extrapyramidal side effects for the treatment of depression in elderly patients with psychotic symptoms. The poor prognostic factors for patients were chronic environmental stress (poverty) and lack of a social support system. Although the patient lived with her children and grandchildren, she rarely received care. Hence, it was not possible to monitor her condition and medication intake. Conclusions : The consensus is that the abrupt discontinuation of short half-life selective serotonin reuptake inhibitors (SSRIs), such as paroxetine can be associated with transient symptomatology, much of which is of a serotonergic nature. Psychotic-like symptoms have also been reported in both controlled trials and large patient databases. [résumé d'auteur] |
| En ligne : | https://www.em-premium.com/article/1537430 |
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